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Dr. Don Thomas, MD

I am Dr. Donald Thomas, MD, a rheumatologist treating hundreds of lupus patients for over 30 years. Read my first blog post here to understand why I started this website and blog about “The Lupus Encyclopedia” and “The Lupus Secrets”.

Dr. Don Thomas also enjoys educating and empowering doctors, medical students, nurses, physician assistants, nurse practitioners, and patients.

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Word Symptoms in Scrabble Tiles

Early Signs of Lupus: What to Look For (May 2025 Update)

We must diagnose systemic lupus erythematosus (SLE) soon after symptoms begin. The quicker we treat SLE, the less
Image that says CAR-T Cells made simple

CAR-T Cell Therapy For Lupus Made Simple (January 2025 UPDATE)

The field of CAR-T therapies in treating autoimmune diseases like lupus is rapidly expanding. As of April 2024,
Graphs showing Lupkynis voclosporin efficacy in lupus nephritis Lancet article

Voclosporin for Lupus Nephritis: Great results in The Lancet

Note the impressively higher response rates in the blue bars (Lupkynis + mycophenolate + steroids) compared to pink
Root cause of lupus research

New Research: A Root Cause of Lupus? [Reported July 2024]

New research claimed they discovered a root cause of lupus. Researchers at Northwestern Medicine and Brigham and Women’s
blood vessels vascular with red blood cells floating inside an artery

Diabetes Drug Pioglitazone Helpful for Lupus [Suggests NIH study]

Lupus Research Article Peroxisome proliferator-activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus This
Lupus related hair loss

Hair and Skin Problems in Lupus [Feb 2025 Update]

Most individuals with systemic lupus erythematosus (SLE) experience skin involvement or hair loss. There are many different types
Lupus and purple spot

Lupus and Purple Spots on Skin

Low platelet counts (thrombocytopenia): Platelets are a type of blood cell that helps blood clot. This protects us
Dry cracked skin

Top Dermatologist Tips For Itchy, Dry Skin in Lupus and Sjögren’s [April 2026 Update]

Unfortunately, dry, itchy skin is a common problem in lupus patients. Most patients try everything they think may
Lupus and the digestive system

Lupus and The Digestive System

Systemic lupus erythematosus (SLE), commonly known as lupus, is an autoimmune disorder that can affect nearly every organ
Dry mouth from lupus and Sjogren

Lupus Can Cause Tooth Decay: How to Prevent Dry Mouth and Cavities (October 2025 Update)

Lupus patients have a high rate of poor dental health and tend to lose their teeth at a
A man with trigger finger due to tenosynovitis

Now Research Shows: Lupus tendinitis, common cause of lupus pain

Th Jaccoud’s arthropathy due to lupus tendinitis (lupus tendonitis) and lupus tenosynovitis What is lupus tendinitis (also spelled
Drawing of an electron microscopic view of the hepatitis C virus

Lupus and Hepatitis C: Lupus Patients Should be Tested for Hepatitis C

The interactions of hepatitis C and systemic lupus is strange, and hepatitis C can mimic lupus … read
Anti-SSA (anti-Ro) in a lupus patient

Anti-SSA Test (anti-Ro): Know Your Labs

Understanding the Anti-SSA (Anti-Ro) Blood Test in Lupus and Sjögren’s Have you recently received a positive anti-SSA blood
sick girl for blog about children with kidney inflammation blog post

Benlysta for pediatric lupus nephritis: FDA-approved

  Benlysta for children with lupus kidney inflammation (lupus nephritis): FDA-approved on July 26, 2022 This is a
Melatonin being produced by the pineal gland in lupus

Melatonin For Lupus May be Good Per the Best Medical Evidence [NEW!]

Melatonin For Lupus: What does the Research Show?         (Updated August 2021) Why do people
Vacation safety with lupus

Traveling With Lupus – Advice From a Rheumatologist

Traveling with systemic lupus erythematosus (SLE) presents its unique challenges. Making sure that you stay as healthy and
Woman who has a malar rash (butterfly rash) due to lupus with lupus disease activity

How Severe is Your Lupus? Use a Lupus Severity Index [May 2025 Update)

Our goal in treating systemic lupus erythematosus is complete remission while using medications that include hydroxychloroquine (if not
Hydroxychloroquine and Plaquenil Top Tips

Top Tips on Taking Hydroxychloroquine for Lupus [April 2026 Update]

Taking hydroxychloroquine for systemic lupus erythematosus (SLE) is considered the most important drug for lupus. It is the
Lennon Wall graffiti in Prague Czech Republic that says Lucy in the Sky with Diamonds

Lupus and “Lucy in the Sky with Diamonds”

What do the following have in common? Lupus A drawing by a 3-year-old Julian Lennon Flowers and gardening
Sea moss along the coast

Sea Moss as a Lupus Prebiotic

Patients ask about Sea Moss as a Lupus Prebiotic: Sea moss was never on my radar until 2022-2023.
X-ray of respiratory system

Lupus and the Respiratory System [March 2025 Update]

The respiratory system, or the pulmonary system, is commonly affected by systemic lupus erythematosus (SLE). This system plays
Medication blister packet

Heparin versus Warfarin for Lupus

Systemic lupus erythematosus (SLE) can lead to blood clots through various mechanisms. In addition, lupus patients are at
Asian woman doctor reading a chest x-ray showing pneumonia

New Pneumonia, Shingles, RSV, and Hepatitis Vaccine Recommendations [2024]

Centers for Disease Control 2024 Vaccine Recommendations In 2024 came out with its new vaccine recommendations. In this
Lupus headaches

Lupus Headaches: Causes, Symptoms, and Treatment [March 2025 Update]

Most systemic lupus erythematosus (SLE) patients get headaches. Are these due to lupus? Or are they due to
Pain from Fibromyalgia

Lupus and Fibromyalgia

Lupus and Fibromyalgia: Understanding the Connection Lupus and fibromyalgia are two distinct conditions, but they often coexist, causing
Two thumbs up

FDA approves Benlysta for lupus nephritis December 2020

Benlysta (belimumab) is the 1st drug ever FDA-approved to treat lupus nephritis ​Historic milestone! ___________________________ NOTE: Johns Hopkins
COVID-19 vaccine for lupus patients

Moderna and Pfizer Vaccines: How Effective is One COVID shot?

CDC Study answers this question Please get your COVID-19 vaccine! We all would like life to go back
Don Thomas, MD answers question about lupus and immune boosting supplements like Echinacea

Vitamins For Lupus: Avoid some is the best advice

Not All Supplements and Vitamins for Lupus Patients are Safe Vitamins for lupus patients: “Ask Dr. T!” question
Newspaper on fire about lupus patients and COVID-19 vaccines

Provocative Advice: Lupus Patients need COVID Vaccines [2021]

Evaluation and recommendations by noted lupus experts: Lupus patients need COVID vaccines Hot off the press from Lupus
Lupus and infections

Lupus and Infections

Lupus infections remain one of the most serious complications for people living with the condition. Chapter 22 of
Herbal supplements for lupus that worsen lupus

Supplements That Worsen Lupus & 6 That Help [March 2025 Update]

Lupus is an autoimmune disease where the immune system is overactive. This post discusses a 2024 research study
Illustration of collecting a urine sample

How to collect a urine sample properly for testing (UPDATED January 2025)

    It is essential for lupus patients to regularly collect an accurate clean catch urine sample  
Low vitamin D levels can make lupus worse

Lupus and Vitamin D Advice: Can be lowest in women of color

Lupus and vitamin D in Women of Color. Why and what to do- “Ask Dr. T!” question of
The endocrine system and lupus

Lupus and The Endocrine System

Lupus, a complex autoimmune condition, impacts various systems in the body, including the endocrine system. The endocrine system
Proteinuria in lupus nephritis. This is what a kidney looks like

Proteinuria in Lupus Nephritis: Video tips and the bottom line [March 2025 UPDATE]

When excessive protein leaks from the kidneys and into the urine, it is called proteinuria. Proteinuria in lupus
Extra COVID vaccines are important for us to prevent infection

Dr. Donald Thomas gets his extra COVID vaccines: It was easy!

UPDATED September 2021: I cannot wait to get my extra COVID vaccines … specifically my 3rd booster shot!
Black middle aged black doctor giving a heavy set white woman with lupus a flu shot

Lupus Flare After Flu Shot? Question of the Day Here

Do Flu Shots Cause Lupus Flares? Lupus flare after flu shot? Question of the day: Dr. Thomas, I
Early signs of lupus in females

Early Signs of Lupus in Females

Lupus, an autoimmune disease, predominantly affects women. Around 90% of lupus patients are women, while 10% are men.
Illustration of a clipboard, doctor and thyroid

Lupus and Thyroid Medications

Lupus and thyroid disease go hand in hand. The thyroid gland is at the front of the neck,
Lupus and pregnancy

Lupus, The Reproductive System, and Pregnancy

Lupus, or systemic lupus erythematosus (SLE), is a complex autoimmune disease that can affect various organs and systems
News Flash COVID-19 vaccine for lupus patients

Covid-19 Vaccine for Lupus Patients: Please get your vaccine

Should We be Recommending the COVID-19 Vaccine for Lupus Patients?: Yes! What I tell my systemic lupus patients
Malar butterfly rash symptom of lupus

Types of Rash in Lupus: A Comprehensive Guide [February 2026 Update]

Lupus patients have many more types of rash than the commonly discussed butterfly rash and discoid lupus. After
White blood cells in urine or pyuria

Lupus and High White Blood Cells in Urine

Elevated white blood cell (WBC) counts can arise in lupus patients for various reasons. This article will delve
Lupus and the Nervous System

Lupus and the Nervous System

Systemic lupus erythematosus (SLE) commonly affects the body’s nerves. Our nerves cause us to be able to feel
Discoid lupus on the chest of a white woman Saphelo for lupus

Saphnelo for Lupus: One of Two Approved Biologics [February 2025 Update]

Anifrolumab (Saphnelo) effectively treats individuals with systemic lupus erythematosus. It reduces the overactivity of an immune system molecule
Microscopic view of a positive fluorescent antinuclear antibody test used to diagnose a lupus patient

Positive ANA workup – Is it lupus or not? [October 2024 Update]

Antinuclear antibodies (ANA) are present in up to 20% of the healthy population, depending upon the particular lab
Man with yellow eyes due to jaundice from hepatitis

Lupus and Hepatitis B Vaccine: Endorsed in the CDC guidelines

Lupus and Hepatitis B Addendum: The recommendations for hepatitis B vaccines changed in 2022. The CDC recommended that
Lupus question should I get a 5th COVID vaccine and Evusheld

Do I need a 5th COVID Vaccine AND Evusheld if I have lupus? [December 2023 UPDATE]

December 2023 Update: Yearly Fall COVID shots and a replacement for Evusheld The coronavirus that causes COVID-19 has
CBD for lupus medical marijuana leaf symbol

CBD for Lupus: Look here for the best advice [2023 Update]

Medical Marijuana (Cannabis, Cannabinoids, THC, CBD for Lupus)? Should patients use CBD or other cannabis products for lupus?
Probiotic supplements and lupus

Lupus and Taking Probiotics/Prebiotics: The truth [Updated JUL ’23]

Lupus and taking probiotics: Should you take probiotics if you have lupus, and what are the best probiotics