Finally, the phase 3 data were published in the Lancet!
Lupkynis (voclosporin) impressively improves lupus nephritis compared to when patients get mycophenolate plus steroids alone.
We can now read the data ourselves, and it is impressive.
Here is where I break down the numbers into easier to understand language:
Here is a link to the article itself:
Treatments are getting better and better for lupus patients. Now, if only anifrolumab (Saphnelo) can get approved ASAP!
Prof Brad H Rovin, MD, et al. Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. The Lancet May 07, 2021 Online; DOI:https://doi.org/10.1016/S0140-6736(21)00578-XDOI
Note that Dr. Thomas' posts are for informational purposes only, and are not meant to be specific medical advice for individuals. Always seek the advice of your healthcare provider with any questions regarding your own medical situation.
DONALD THOMAS, MD