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Research Studies in Lupus

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Dr. Don Thomas, MD

I am Dr. Donald Thomas, MD, a rheumatologist treating hundreds of lupus patients for over 30 years. Read my first blog post here to understand why I started this website and blog about “The Lupus Encyclopedia” and “The Lupus Secrets”.

Dr. Don Thomas also enjoys educating and empowering doctors, medical students, nurses, physician assistants, nurse practitioners, and patients.

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Lupus Mottled Skin

Lupus Mottled Skin & Symptoms (Feb 2025 Update)

One skin issue associated with systemic lupus erythematosus (SLE) is “mottled skin,” with livedo reticularis being one of
Hydroxychloroquine and Plaquenil Top Tips

Top Tips on Taking Hydroxychloroquine for Lupus [Updated April 2025]

Taking hydroxychloroquine for systemic lupus erythematosus (SLE) is considered the most important drug for lupus. It is the
A lupus patient with Jaccoud

Lupus Tendonitis: A Common Cause of Pain in Lupus Patients

https://www.lupusencyclopedia.com/book-photos/#tendon…
White woman doctor giving female lupus patient a flu shot

10 Reasons Not to Get a Flu Shot: Learn the Truth Now!

10 Reasons Not to Get a Flu Shot: The Flu Shot is a Life-Saver for Lupus Patients, Other
Lupus life expectancy

Understanding Lupus Life Expectancy [Feb 2025 Update]

Dr. Thomas has systemic lupus erythematosus (SLE) patients in their 70s, 80s, and 90s! Living with lupus is
Increase energy with lupus

Increase Energy with Lupus ([February 2025 Update]

Did you know that energy loss is the most common disabling problem in people living with systemic lupus
A mask, needle, and syringe as symbols to protect from COVID-19

What is Evusheld and Who Should Get Evusheld: Prevent COVID-19 [OCT 2022 Update]

What is Evusheld? It is a treatment to prevent COVID-19 infections. It is not a vaccine. It is
Dry cracked skin

Top Dermatologist Tips For Itchy, Dry Skin in Lupus and Sjögren’s [October 2024 Update]

Unfortunately, dry, itchy skin is a common problem in lupus patients. Most patients try everything they think may
Discoid lupus erythematosus on the cheek of a white woman with systemic lupus

Can Discoid Lupus Turn into Systemic?- “Sure” Now more about the truth

The Latest Research Answers the Question: “Can discoid lupus turn into systemic lupus erythematosus?” Discoid lupus: note the
sick girl for blog about children with kidney inflammation blog post

Benlysta for pediatric lupus nephritis: FDA-approved

  Benlysta for children with lupus kidney inflammation (lupus nephritis): FDA-approved on July 26, 2022 This is a
Lupus related hair loss

Hair and Skin Problems in Lupus [Feb 2025 Update]

Most individuals with systemic lupus erythematosus (SLE) experience skin involvement or hair loss. There are many different types
COVID-19 vaccine for lupus patients

Moderna and Pfizer Vaccines: How Effective is One COVID shot?

CDC Study answers this question Please get your COVID-19 vaccine! We all would like life to go back
Drawing of an electron microscopic view of the hepatitis C virus

Lupus and Hepatitis C: Lupus Patients Should be Tested for Hepatitis C

The interactions of hepatitis C and systemic lupus is strange, and hepatitis C can mimic lupus … read
Survey about being diagnosed with lupus and The Lupus Foundation of America

Participate in this lupus survey if you live in the USA [Survey is closed]

The Lupus Foundation of America wants to learn more about the difficulties in being diagnosed with lupus Click
Lupus patient with COVID coronavirus

Getting the COVID-19 Vaccine: Now see me excited to get it

What was it like getting the COVID-19 vaccine? … and some advice for lupus patients   A rheumatology
Malar butterfly rash symptom of lupus

Types of Rash in Lupus: A Comprehensive Guide [March 2025 Update]

Lupus patients have many more types of rash than the commonly discussed butterfly rash and discoid lupus. After
Woman with Sjogren

Research Results in Dealing with Autoimmune Disease Fatigue Now

The causes of fatigue and dealing with autoimmune disease fatigue. ​ Tips on how to improve energy with
Low vitamin D levels can make lupus worse

Lupus and Vitamin D Advice: Can be lowest in women of color

Lupus and vitamin D in Women of Color. Why and what to do- “Ask Dr. T!” question of
wrist brace for joint protection for the wrist with lupus arthritis

Joint Protection Advice for Lupus Arthritis

Joint Protection Advice for Lupus Arthritis Joint protection is essential in dealing with pain. When you rest a
Lupus, the Heart and Blood Vessels

Lupus, the Heart and Blood Vessels [March 2025 Update]

Lupus can significantly impact the heart and blood vessels, known as the cardiovascular system. This article goes into
Type 1 interferon cytokines are inhibited by the anifrolumab FDA approval drug

Anifrolumab FDA Approval to Treat Systemic Lupus [Saphnelo February 2025 Update]

Anifrolumab (Saphnelo) is the 2nd FDA-approved biologic to treat systemic lupus erythematosus (SLE). The first biologic was belimumab
Anti-inflammatory diet for lupus and autoimmune diseases

Anti-inflammatory Diet for Autoimmune Disease: New Research (AI Protocol)

The Autoimmune Protocol (AI protocol) is another term for the anti-inflammatory diet. The chart below was shown to
CBD for lupus medical marijuana leaf symbol

CBD for Lupus: Look here for the best advice [2023 Update]

Medical Marijuana (Cannabis, Cannabinoids, THC, CBD for Lupus)? Should patients use CBD or other cannabis products for lupus?
Melatonin being produced by the pineal gland in lupus

Melatonin For Lupus May be Good Per the Best Medical Evidence [NEW!]

Melatonin For Lupus: What does the Research Show?         (Updated August 2021) Why do people
Lupus and the digestive system

Lupus and The Digestive System

Systemic lupus erythematosus (SLE), commonly known as lupus, is an autoimmune disorder that can affect nearly every organ
Bisphosphonate drugs and lupus

Bisphosphonate Drugs and Lupus

Many SLE patients have fractures in their spine (vertebral fractures), and around half do not realize it. After
Graphs showing Lupkynis voclosporin efficacy in lupus nephritis Lancet article

Voclosporin for Lupus Nephritis: Great results in The Lancet

Note the impressively higher response rates in the blue bars (Lupkynis + mycophenolate + steroids) compared to pink
Male lupus patient with a mask

“Do I need a mask after vaccination?” Now here is the truth

Please continue to protect yourself as you did before if you have lupus or another systemic autoimmune disease
Benlysta is FDA approved to treat lupus nephritis

Benlysta approved for lupus nephritis: is it for mild cases?

Lupus Question of The Day: Is Benlysta for mild lupus nephritis? Ask Dr. T question and shortened answer
Urticaria hives allergic reaction in systemic lupus erythematosus SLE

Allergies and Itching after COVID vaccine? Announcing Research Here

Results from 64,900 vaccines: How often are allergies and itching after COVID vaccine? We’ll take a look at
Image that says CAR-T Cells made simple

CAR-T Cell Therapy For Lupus Made Simple (January 2025 UPDATE)

The field of CAR-T therapies in treating autoimmune diseases like lupus is rapidly expanding. As of April 2024,
Covid Study Flyer

COVID Vaccine and Lupus: Join in a Research Study Now

How the COVID Vaccine and Lupus Interact is Important to Figure Out: Consider Joining this NIH Research Study
treatment of lupus showing a lot of pills tablets and capsules

Treatment of Lupus: Best Practices & Guidelines [Mar ’25 Update]

The treatment of lupus has improved significantly over the past decade. Most patients can expect to go into
Man with lupus with hands on his chest during a heart attack

Bottom Line on Diabetes vs Lupus and Stroke & Heart Attacks

Lupus and Stroke and Heart Attacks: A bigger problem than we thought! We have known for a long
Connective Tissue Disease written on a white board by a doctor

Undifferentiated Connective Tissue Disease: It Is Real! (Feb 2025 Update)

Undifferentiated connective tissue disease (UCTD) is one of the most common diagnoses made by rheumatologists. Many systemic lupus
Immunosuppressants and COVID vaccine ACR guidelines and recommendations

Immunosuppressants and COVID Vaccine: Fundamentals in the new guidelines

Immunosuppressants and COVID vaccine: which you should stop and not stop American College of Rheumatology Clinical Guidance Summary UPDATED
Lupus and hives on arm

Lupus and Hives

Systemic lupus erythematosus (SLE) can cause hives (also called urticaria). Hives are itchy, swollen bumps that appear on
Questions about lupus treatments and living with lupus

Living With Lupus Blog: The Lupus Encyclopedia – Q & A Video

Dr. Donald Thomas Answers Lupus Patients’ Questions on His Living With Lupus Blog: The Lupus Encyclopedia Watch this
Woman holding thermometer to head during what is a lupus flare

What is a Lupus Flare: Prevent and Treat [March 2025 Update]

Did you know that even mild to moderate lupus flares are associated with a two-fold increased risk of
Lupus and pregnancy

Lupus, The Reproductive System, and Pregnancy

Lupus, or systemic lupus erythematosus (SLE), is a complex autoimmune disease that can affect various organs and systems
Discoid lupus causing scarring alopecia

How to Stop Lupus Hair Loss:

How to stop lupus hair loss! – Yes! You can do things to help! And learn that much
VA disability for lupus

VA Disability for Lupus: Navigating Your Claim [Feb 2025 Update]

Startling statistic: A large study showed that Afghanistan and Iraqi veterans suffering from PTSD were twice as likely
X-ray of respiratory system

Lupus and the Respiratory System [March 2025 Update]

The respiratory system, or the pulmonary system, is commonly affected by systemic lupus erythematosus (SLE). This system plays
Anti-chromatin antibodies attach to chromatin in lupus patients

Chromatin antibody: Make sure you know your labs

Some systemic lupus erythematosus (SLE) are positive for anti-chromatin antibodies. This is an interesting antibody that has some
exercise and lupus photo of a woman on a stationary bicycle

Weight Loss & Exercise in Lupus: the science & patient view [March 2025 Update]

Weight loss & exercise provide many benefits to lupus patients. Healthcare providers consider exercise as “free medication” with
Dr. Donald Thomas MD holding the new edition Lupus Encyclopedia A Comprehensive Guide for Patients and Health Care Providers

The Lupus Encyclopedia, edition 2: Now Available!

The Lupus Encyclopedia, edition 2: A Comprehensive Guide for Patients and Health Care Providers is now available at
Lupus and purple spot

Lupus and Purple Spots on Skin

Low platelet counts (thrombocytopenia): Platelets are a type of blood cell that helps blood clot. This protects us
Sea moss along the coast

Sea Moss as a Lupus Prebiotic

Patients ask about Sea Moss as a Lupus Prebiotic: Sea moss was never on my radar until 2022-2023.
Lupus and the urinary system

Lupus and the Urinary System [March 2025 Update]

Kidney inflammation (lupus nephritis) occurs in around 45% of people who have systemic lupus erythematosus (SLE). Therefore, lupus
Black middle aged black doctor giving a heavy set white woman with lupus a flu shot

Lupus Flare After Flu Shot? Question of the Day Here

Do Flu Shots Cause Lupus Flares? Lupus flare after flu shot? Question of the day: Dr. Thomas, I